Zeng-jie Yang
Department of Cancer research
Fox Chase Cancer Center
United States of America
Biography
Zeng-jie Yang,Educational Background: Post Doc, Cancer Biology, Duke University Medical Center, 2005-2010. PhD, Neurogenetics, University of Nottingham, 2005. MS, Genetics, Fudan University Medical Center, 2000. MD, North China Coal Medical University, 1997.
Research Interest
Cellular origins for patched-associated medulloblastoma. Identification of the subset of patched-deleted cells with increased tumorigenic potential. Stromal cells in tumor progression.
Publications
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Yang, Z. J., Ellis, T., Markant, S. L., Read, T. A., Kessler, J. D., Bourboulas, M., ... & Wainwright, B. J. (2008). Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells. Cancer cell, 14(2), 135-145.
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Kessler, J. D., Hasegawa, H., Brun, S. N., Emmenegger, B. A., Yang, Z. J., Dutton, J. W., ... & Wechsler-Reya, R. J. (2009). N-myc alters the fate of preneoplastic cells in a mouse model of medulloblastoma. Genes & development, 23(2), 157-170.
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Li, P., Du, F., Yuelling, L. W., Lin, T., Muradimova, R. E., Tricarico, R., ... & Yang, Z. J. (2013). A population of Nestin-expressing progenitors in the cerebellum exhibits increased tumorigenicity. Nature neuroscience, 16(12), 1737-1744.
