Derek Stirewalt
Associate Professor
oncology
Fred Hutchinson Cancer Rearch Center
United States of America
Biography
Dr. Stirewalt earned his Bachelor's degree from Davidson College in 1988 and his M.D. from the University of North Carolina at Chapel Hill Medical School in 1992, where he also completed his internship and residency in internal medicine. He subsequently completed an Oncology Fellowship at the FHCRC/UW in 1999. After this fellowship, he was offered and accepted a faculty position at the FHCRC with a joint appointment at the UW. He has remained at the FHCRC since that time. Dr. Stirewalt currently holds an appointment as an associate professor at University of Washington and associate member at the Fred Hutchinson Cancer Research Center. Over his tenure at FHCRC and UW, he has become a very active member of the faculty – residing on or overseeing multiple committees such as IRB, FHCRC Clinical Division Appointments Committee, chair of the Nonmyeloablative Transplant Committee, and director of the FHCRC/UW Leukemia Repository.
Research Interest
Dr. Stirewalt’s research examines the biology of acute myeloid leukemia (AML) biomarkers and methods to use these biomarkers to improve the care of patients with this disease. This research has been funded through independent awards from NIH and other agencies. He is a nationally-recognized as a leader in the field of AML biomarker research, having extensive experience in the design, methods and analyses of quantitative RT/PCR assays, mutation studies, RNA profiling and novel RNA. His work has led to publications in Nature Cancer Review, Blood, and Leukemia on these topics, as well as, strong collaborations with other leaders in this field. In addition, he currently serves on several national committees or grant reviews such as Southwest Oncology Leukemia Committee and American Federation of Aging Research National Advisory Grant Review Group
Publications
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Hsu C-H, Nguyen C, Yan C, Ries RE, Chen Q-R, Hu Y, Ostronoff F, Stirewalt DL, Komatsoulis G, Levy S et al.. 2015. Transcriptome Profiling of Pediatric Core Binding Factor AML.. PloS one. 10(9):e0138782
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Qu X, Davison J, Du L, Storer B, Stirewalt DL, Heimfeld S, Estey E, Appelbaum FR, Fang M. 2015. Identification of Differentially Methylated Markers among Cytogenetic Risk Groups of Acute Myeloid Leukemia.. Epigenetics : official journal of the DNA Methylation Society. 10(6):526-35.
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Ostronoff F, Othus M, Lazenby M, Estey E, Appelbaum FR, Evans A, Godwin J, Gilkes A, Kopecky KJ, Burnett A et al.. 2015. Prognostic significance of NPM1 mutations in the absence of FLT3-internal tandem duplication in older patients with acute myeloid leukemia: a SWOG and UK National Cancer Research Institute/Medical Research Council report.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 33(10):1157-64
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VanderWalde N, Jagsi R, Dotan E, Baumgartner J, Browner IS, Burhenn P, Cohen HJ, Edil BH, Edwards B, Extermann M et al.. 2016. NCCN Guidelines Insights: Older Adult Oncology, Version 2.2016.. Journal of the National Comprehensive Cancer Network : JNCCN. 14(11):1357-1370.