Paul Catalano
Senior Lecturer
Department of Biostatistics
Harward School Of Public Health
United States of America
Biography
Sc.D., 1991, Harvard School of Public Health
Research Interest
Dr. Catalano’s major interests involve research in methods for the analysis of multiple outcomes and repeated measures and their application to environmental dose-response modeling and quantitative risk assessment. In particular, he has developed models for the analysis of data from developmental and neurological toxicity studies in animals, where interest centers on characterization of the dose-response profile for a variety of adverse outcomes such as fetal death, a variety of developmental alterations, and lowered birth weight. In addition to providing valuable information on the quantitative relationship between exposure and adverse health effects, such models can be used to estimate a dose level corresponding to a specified arbitrary level of overall risk above background. These levels are useful in helping to understand risk to humans. The statistical analysis of data from such studies is complicated because the outcomes are composed of clusters of multivariate continuous and binary responses, requiring methods for repeated measures that incorporate multiple data types.
Publications
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Regan MM, Catalano PJ. Regression models for mixed discrete and continuous outcomes with clustering. Risk Analysis 2000; 20(3):363-376.
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Regan MM, Catalano PJ. Bivariate dose-response modeling and risk estimation in developmental toxicology. Journal of Agricultural, Biological and Environmental Statistics 1999; 4:217-237.
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Regan MM, Catalano PJ. Likelihood models for clustered binary and continuous outcomes: Application to developmental toxicology. Biometrics 1999; 55:760-768.
