Carol S. Lim
Professor
Department of Pharmaceutics and Pharmaceutical Chemistry
Huntsman Cancer Institute
United States of America
Biography
Carol Lim, PhD, is an associate professor in the Departments of Pharmaceutics and Pharmaceutical Chemistry at the University of Utah and a member of the Cell Response and Regulation Program at Huntsman Cancer Institute.Lim studies subcellular mislocalization of proteins, which is a cellular process that can result in cancer. She hopes to understand why mislocalizations occur and establish therapeutic methods to address the consequences. She also has a general interest in breast cancer and leukemia.Lim received a bachelor's degree from Purdue University, Indiana, and a PhD from the University of California, San Francisco.
Research Interest
Gene Therapy Peptides Cancer Therapeutic Development Tumor Suppressor Proteins DNA/Gene Targeted Therapeutics Gene Expression Regulation Cellular Kinetics Nuclear Import and Export
Publications
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Matissek KJ, Okal A, Mossalam M, Lim CS (2014). Delivery of a monomeric p53 subdomain with mitochondrial targeting signals from pro-apoptotic Bak or Bax. Pharm Res, 31(9), 2503-15.
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Bruno BJ, Lim CS (2015). Inhibition of bcr-abl in human leukemic cells with a coiled-coil protein delivered by a leukemia-specific cell-penetrating Peptide. Mol Pharm, 12(5), 1412-21.
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Woessner DW, Eiring AM, Bruno BJ, Zabriskie MS, Reynolds KR, Miller GD, OHare T, Deininger MW, Lim CS (2015). A coiled-coil mimetic intercepts BCR-ABL1 dimerization in native and kinase-mutant chronic myeloid leukemia. Leukemia, 29(8), 1668-75.
