Cynthia Burrows
Professor
Department of Chemistry
Huntsman Cancer Institute
United States of America
Biography
Cynthia Burrows, PhD, is a distinguished professor in the Department of Chemistry at the University of Utah and a member of the Nuclear Control of Cell Growth and Differentiation Program at Huntsman Cancer Institute.Burrows studies chemical processes that result in the formation of mutations. Mutations in DNA result in cancer, so by understanding how mutations develop, researchers hope to find ways to prevent them.Burrows was awarded the Arthur C. Cope Scholar Award from the American Chemical Society. She received a bachelor's degree from the University of Colorado, Boulder, and a PhD from Cornell University, New York.
Research Interest
DNA Sequencing Technology DNA Damage Origins of Life
Publications
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Fleming AM, Orendt AM, He Y, Zhu J, Dukor RK, Burrows CJ (2013). Reconciliation of chemical, enzymatic, spectroscopic and computational data to assign the absolute configuration of the DNA base lesion spiroiminodihydantoin. J Am Chem Soc, 135(48), 18191-204.
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Wolna AH, Fleming AM, An N, He L, White HS, Burrows CJ (2013). Electrical Current Signatures of DNA Base Modifications in Single Molecules Immobilized in the alpha-Hemolysin Ion Channel. Isr J Chem, 53(6-7), 417-430.
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McKibbin PL, Fleming AM, Towheed MA, Van Houten B, Burrows CJ, David SS (2013). Repair of hydantoin lesions and their amine adducts in DNA by base and nucleotide excision repair. J Am Chem Soc, 135(37), 13851-61.
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Zhou J, Liu M, Fleming AM, Burrows CJ, Wallace SS (2013). Neil3 and NEIL1 DNA glycosylases remove oxidative damages from quadruplex DNA and exhibit preferences for lesions in the telomeric sequence context. J Biol Chem, 288(38), 27263-72.
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Fleming AM, Burrows CJ (2013). G-quadruplex folds of the human telomere sequence alter the site reactivity and reaction pathway of guanine oxidation compared to duplex DNA. Chem Res Toxicol, 26(4), 593-607.
