Dennis C. Shrieve

Biography

Dennis C. Shrieve, MD, PhD, is the Rudolph S. and Edna Reese Research Professor and chair of the Department of Radiation Oncology at the University of Utah School of Medicine. He is a member of the Experimental Therapeutics Program at the Huntsman Cancer Institute and co-director of the Stereotactic Radiosurgery Program at the University. Shrieve is board certified by the American Board of Radiology in Radiation Oncology and has primary clinical research interests in adult and pediatric neuro-oncology, pediatric radiation oncology, and stereotactic radiotherapy. His basic research interests include intrinsic radiosensitivity of human tumors, the mechanisms of intrinsic cellular resistance to radiation and chemotherapy, and combined chemotherapy/radiotherapy. Shrieve serves on the Board of Trustees of the American Board of Radiology and is past-President of the International Stereotactic Radiosurgery Society. He is a member of the NCCN Tumors of the Central Nervous System Panel of Experts. Shrieve received his MD from the University of Miami and his PhD in radiation biophysics from the University of California at Berkeley. He served on the faculties of the University of California, San Francisco, and Harvard Medical School before coming to the University of Utah. Shrieve is the author or co-author of over 150 articles or book chapters in the medical and scientific literature. He co-editied the book "Human Radiation Injury" in 2010.  

Research Interest

Adult and pediatric neuro-oncology Pediatric Radiation Oncology Conformal radiotherapy and radiosurgery for intracranial tumors of children and adults Radiotherapy using altered fractionation in the treatment of pediatric and adult tumors Combined chemoradiotherapy Genitourinary malignancies Intrinsic radiosensitivity of human tumors Mechanisms of intrinsic cellular resistance to radiation and chemotherapy Role of microenvironmental factors on cellular sensitivity to radiation and to chemotherapeutic agents Mechanisms of normal tissue injury and repair following radiotherapy