John R. Hoidal
Professor
Department of Medicine
Huntsman Cancer Institute
United States of America
Biography
John Hoidal, MD, is a professor and chair of the Department of Medicine at the University of Utah and an investigator of the Huntsman Cancer Institute. He holds the Clarence M. and Ruth N. Birrer Presidential Endowed Chair. His research focuses on the genetic and molecular bases for nicotine addiction and the consequences of cigarette smoking. By gaining insights into biochemical pathways of addiction and ways to modify them, Hoidal hopes to find better ways to prevent and treat nicotine addiction and reduce the risk of smoking-related diseases such as lung cancer. Hoidal received a bachelor's degree from Jamestown College, North Dakota, and a medical degree from the University of Minnesota.
Research Interest
Pulmonary Medicine Internal Medicine Health Sciences
Publications
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Ismail S, Sturrock A, Wu P, Cahill B, Norman K, Huecksteadt T, Sanders K, Kennedy T, Hoidal J (2009). NOX4 mediates hypoxia-induced proliferation of human pulmonary artery smooth muscle cells: the role of autocrine production of transforming growth factor-{beta}1 and insulin-like growth factor binding protein-3. Am J Physiol Lung Cell Mol Physiol, 296(3), L489-99.
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Chen Y, Hao H, He S, Cai L, Li Y, Hu S, Ye D, Hoidal J, Wu P, Chen X (2010). Lipoxin A4 and its analogue suppress the tumor growth of transplanted H22 in mice: the role of antiangiogenesis. Mol Cancer Ther, 9(8), 2164-74.
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Reynolds PR, Kasteler SD, Schmitt RE, Hoidal JR (2011). Receptor for advanced glycation end-products signals through Ras during tobacco smoke-induced pulmonary inflammation. Am J Respir Cell Mol Biol, 45(2), 411-8.
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Jin H, Webb-Robertson BJ, Peterson ES, Tan R, Bigelow DJ, Scholand MB, Hoidal JR, Pounds JG, Zangar RC (2011). Smoking, COPD, and 3-nitrotyrosine levels of plasma proteins. Environ Health Perspect, 119(9), 1314-20.
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Liou TG, Adler FR, Keogh RH, Li Y, Jensen JL, Walsh W, Packer K, Clark T, Carveth H, Chen J, Rogers SL, Lane C, Moore J, Sturrock A, Paine R 3rd, Cox DR, Hoidal JR (2012). Sputum biomarkers and the prediction of clinical outcomes in patients with cystic fibrosis. PLoS One, 7(8), e42748.
