Katharine S. Ullman
Professor
Department of Oncological Sciences
Huntsman Cancer Institute
United States of America
Biography
Huntsman Cancer Institute (HCI) investigator Katharine Ullman, PhD, is a professor in the Department of Oncological Sciences at the University of Utah School of Medicine, an adjunct professor in the Department of Biochemistry at the University of Utah, and a member of the Cell Response and Regulation Program. She began serving as the Associate Dean of the Graduate School at the University of Utah in 2016. Ullman and her research team focus on the coordination of cell division, with a particular interest in how disassembly and assembly of nuclear architecture is integrated with other events of cell division. The nucleus harbors a specialized environment, optimized to protect and regulate the cell's DNA. Mis-coordination of cellular remodeling during division leaves the DNA vulnerable to damage and mis-regulation. Elucidating this aspect of cell cycle control opens a new avenue to understanding cell function and how mistakes in division may contribute to tumorigenesis. Ullman earned a PhD from Stanford University before going to the University of California at San Diego for her postdoctoral studies, which were funded in part by the American Cancer Society. She is a recipient of a Burroughs Wellcome Career Award in the Biomedical Sciences and a Scholar award from the Leukemia and Lymphoma Society.
Research Interest
Breast Cancer Cancer Biomarkers Cell Division Cytokinesis Nuclear Pore Complex
Publications
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Makise M, Mackay DR, Elgort S, Shankaran SS, Adam SA, Ullman KS (2012). The Nup153-Nup50 protein interface and its role in nuclear import. J Biol Chem, 287(46), 38515-22.
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Chow KH, Elgort S, Dasso M, Powers MA, Ullman KS (2014). The SUMO proteases SENP1 and SENP2 play a critical role in nucleoporin homeostasis and nuclear pore complex function. Mol Biol Cell, 25(1), 160-8.
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Fay MM, Clegg JM, Uchida KA, Powers MA, Ullman KS (2014). Enhanced arginine methylation of programmed cell death 4 protein during nutrient deprivation promotes tumor cell viability. J Biol Chem, 289(25), 17541-52.
