Mario R. Capecchi
Professor
Department of Human Genetics
Huntsman Cancer Institute
United States of America
Biography
Mario Capecchi, PhD, is a professor in the Department of Human Genetics and adjunct professor in the Department of Oncological Sciences at the University of Utah. He is an investigator of the Howard Hughes Medical Institute, an active participant in the Sarcoma Services Program at Huntsman Cancer Institute, and member of the Nuclear Control of Cell Growth and Differentiation Program.Capecchi studies cancer models (experimental versions of cancer) recreated in mice. In 2007, Capecchi was awarded the Nobel Prize in Medicine/Physiology for his contributions to the development of "mouse knockout technology." He has a particular interest in the study of sarcomas and focuses on unraveling the function of Hox, associated with cancer.Capecchi received a bachelor's degree from Antioch College, Ohio, and a PhD from Harvard University, Massachusetts.
Research Interest
Molecular Genetics Cancer
Publications
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Sen Wu, Guoxin Ying, Qiang Wu& Mario R Capecchi (2007) Toward simpler and faster genome-wide mutagenesis in mice. Nature Genetics.
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Greer, Joy M; Puetz, John; Thomas, Kirk R; Capecchi, Mario R (2000) Maintenance of functional equivalence during paralogous Hox gene evolution.Nature; London.
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Mario R. Capecchi(2005)Gene targeting in mice: functional analysis of the mammalian genome for the twenty-first century.Nature Reviews Genetics 6: 507-512.
