Michael E. Engel
Professor
Department of Pediatric Hematology/Oncology
Huntsman Cancer Institute
United States of America
Biography
Michael Engel, MD, PhD, attended the Vanderbilt University School of Medicine in Nashville, TN. He completed his Pediatric residency training and subspecialty training in Pediatric Hematology/Oncology at the Monroe Carell Jr. Children's Hospital at Vanderbilt. He recently joined the faculty of the University of Utah School of Medicine and Primary Children's Medical Center as Assistant Professor in the Division of Pediatric Hematology/Oncology and as Adjunct Assistant Professor in the Department of Oncological Sciences of the Huntsman Cancer Institute. Dr. Engel's clinical interests encompass hematologic and oncologic illness in children, adolescents and young adults, with an emphasis on hematologic malignancies including myeloid and lymphoid leukemias.
Research Interest
Pediatric Hematology/Oncology
Publications
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Bhowmick NA, Ghiassi M, Bakin A, Aakre M, Lundquist CA, Engel ME, Arteaga CL, Moses HL (2001). Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism. Mol Biol Cell, 12(1), 27-36.
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Engel ME, Hickstein DD, Bauer TR Jr, Calder C, Manes B, Frangoul H (2006). Matched unrelated bone marrow transplantation with reduced-intensity conditioning for leukocyte adhesion deficiency. Bone Marrow Transplant, 37(7), 717-8.
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Frangoul H, Wills M, Crossno C, Engel M, Domm J (2007). Acyclovir-resistant herpes simplex virus pneumonia post-unrelated stem cell transplantation: a word of caution. Pediatr Transplant, 11(8), 942-4.
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Chyla BJ, Moreno-Miralles I, Steapleton MA, Thompson MA, Bhaskara S, Engel M, Hiebert SW (2008). Deletion of Mtg16, a target of t(16;21), alters hematopoietic progenitor cell proliferation and lineage allocation. Mol Cell Biol, 28(20), 6234-47.
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Engel ME, Nguyen HN, Mariotti J, Hunt A, Hiebert SW (2010). Myeloid translocation gene 16 (MTG16) interacts with Notch transcription complex components to integrate Notch signaling in hematopoietic cell fate specification. Mol Cell Biol, 30(7), 1852-63.
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Fagan E, Slone J, Shoemaker A, Black J, Berlin J, Engel ME (April 2012). Neuroendocrine carcinoma in an adolescent with hypercortisolemia. J Pediatr Hematol Oncol, 34(3), 117-119.
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Barrett CW, Smith JJ, Lu LC, Markham N, Stengel KR, Short SP, Zhang B, Hunt AA, Fingleton BM, Carnahan RH, Engel ME, Chen X, Beauchamp RD, Wilson KT, Hiebert SW, Reynolds AB, Williams CS (2012). Kaiso directs the transcriptional corepressor MTG16 to the Kaiso binding site in target promoters. PLoS One, 7(12), e51205.
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Mixon BA, Eckrich MJ, Lowas S, Engel ME (2013). Vincristine, irinotecan, and temozolomide for treatment of relapsed alveolar rhabdomyosarcoma. J Pediatr Hematol Oncol, 35(4), e163-6.
