Dani Dumitriu
ASSISTANT PROFESSOR
Neuroscience
Icahn School of Medicine at Mount Sinai
United States of America
Biography
I am currently conducting independent basic science research while simultaneously completing a residency in General Pediatrics at Mount Sinai. My research focuses on understanding the neurobiological basis for resilience, i.e. the brain wiring that gives some individuals the ability to withstand adversity. Currently, my lab is working on a mouse model of social defeat and developing predictive measures of resilience using a combination of behavioral tasks, high resolution confocal microscopy, and resting state fRMI. My ultimate goal is to pioneer "developmental neuroprevention" by creating tools that will enhance resiliency neural networks in children, thereby leading to happier, healthier lives. Multi-Disciplinary Training Area Neuroscience [NEU] Education BS, University of California, Santa Barbara MD/PhD, Icahn School of Medicine at Mount Sinai
Research Interest
Behavior, Brain Imaging, Cerebral Cortex, Cognitive Neuroscience, Computational Neuroscience, Depression, Image Analysis, Neural Networks, Neurobiology, Neuroscience, Neurotoxicology, Prefrontal Cortex, Quantitative Neuroanatomy, Synapses, Synaptic Plasticity
Publications
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Russo SJ, Dietz DM, Dumitriu D, Morrison JH, Malenka RC, etal (2010) The addicted synapse: mechanisms of synaptic and structural plasticity in nucleus accumbens. Trends in Neurosciences Vol: 33.
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Dumitriu D, Rapp PR, McEwen BS, Morrison JH (2010) Estrogen and the aging brain: an elixir for the weary cortical network. Annals of the New York Academy of Sciences.
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Christoffel DJ, Golden SA, Dumitriu D, Robison AJ, Janssen WG, etal (2011) IκB kinase regulates social defeat stress-induced synaptic and behavioral plasticity. The Journal of Neuroscience Vol: 31.
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Dumitriu D, Rodriguez A, Morrison JH (2011) High-throughput, detailed, cell-specific neuroanatomy of dendritic spines using microinjection and confocal microscopy. Nature Protocols Vol: 6.
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Dumitriu D, Laplant Q, Grossman YS, Dias C, Janssen WG, etal (2012) Subregional, dendritic compartment, and spine subtype specificity in cocaine regulation of dendritic spines in the nucleus accumbens. The Journal of Neuroscience Vol: 32.
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Dumitriu D (2012) Right Brain: past medical story. Neurology Vol: 79.
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Dumitriu D, Berger SI, Hamo C, Hara Y, Bailey M, etal (2012) Vamping: stereology-based automated quantification of fluorescent puncta size and density. Journal of Neuroscience Methods Vol: 209.
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Pereira AC, Lambert HK, Grossman YS, Dumitriu D, Waldman R, etal (2014) Glutamatergic regulation prevents hippocampal-dependent age-related cognitive decline through dendritic spine clustering. Proc Natl Acad Sci VOL: 111.
