Ian S Maze
ASSISTANT PROFESSOR
Pharmacological Sciences, Neuroscience
Icahn School of Medicine at Mount Sinai
United States of America
Biography
Ian S. Maze, Ph.D., is a neurobiologist with extensive training in the molecular biology and chromatin biochemistry of histone regulation in the mammalian central nervous system. His multidisciplinary and integrative research involves the use of biochemical, biophysical, physiological and behavioral analyses to explore the molecular underpinnings of neurodevelopmental and adult cognitive and psychiatric disorders. Dr. Maze is actively investigating the brains of rodents and postmortem humans, as well as human iPSC-derived neurons, to uncover chromatin-based mechanisms of neurological disease. Multi-Disciplinary Training Areas Biophysics and Systems Pharmacology [BSP], Developmental and Stem Cell Biology [DSCB], Neuroscience [NEU] Education BS, The Ohio State University PhD, Mount Sinai School of Medicine Postdoctoral Fellowship, The Rockefeller University
Research Interest
Addiction, Behavior, Chromatin, Depression, Drug Design and Discovery, Gene Expressions, Molecular Biology, Neuroscience
Publications
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Bagot RC, Parise EM, Peña CJ, Zhang HX, Maze I, etal (2015) Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression. Nature communications Vol: 6.
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Maze I, Wenderski W, Noh KM, Bagot RC, Tzavaras N, etal (2015) Critical Role of Histone Turnover in Neuronal Transcription and Plasticity. Neuron Vol: 87.
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Sun H, Damez-Werno DM, Scobie KN, Shao NY, Dias C, etal (2015) ACF chromatin-remodeling complex mediates stress-induced depressive-like behavior. Nature medicine Vol: 21.
