Neurology
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Isabelle M Germano

Professor
Neurosurgery,Neurology,Oncological Sciences
Icahn School of Medicine at Mount Sinai
United States of America

Biography

Dr. Germano joined the faculty at Mount Sinai in 1993. She is Director of The Mount Sinai Comprehensive Brain Tumor Program, an advanced multidisciplinary program based on computer-assisted image-guided neurosurgery and brain mapping to accomplish minimally invasive procedures and treatment of brain tumors, and is Co-director of the Radiosurgery Program. You can learn more about Dr. Germano by visiting the Neurosurgery Tumors website. Her specialty interests include Brain Tumors, Computer-Assisted Image-Guided Neurosurgery, Epilepsy surgery and Radiosurgery. She is Director of The Mount Sinai Medical Center Comprehensive Brain Tumor Program, an advanced multidisciplinary program based on computer-assisted image-guided neurosurgery and brain mapping to accomplish minimally invasive procedures and treatment of brain tumors. Dr. Germano is one of the pioneers of computer-assisted image-guided neurosurgery. This sophisticated technology, including the Novalis Shaped Beam Surgery, is used to perform minimally invasive surgery for patients with brain tumors, epilepsy, Parkinson's disease and movement disorders. Active in national neurosurgery organizations, she has served as an executive committee member for the Congress of Neurosurgery (CNS), as a Board of Directors' member for the American Association of Neurological Surgeons, as an executive committee member of the AANS/CNS Joint Section on Tumors, and as a scientific program member for the AANS, CNS, and the American Epilepsy Society. For the past five years she has directed a course, Advanced Techniques in Image-Guided Brain and Spine Surgery, for neurosurgeons from around the country.In the News Dr. Germano and her work diagnosing and treating brain tumors were recently profiled in The Daily News feature The Daily Check Up. View the PDF. Certifications Neurological Surgery Clinical Focus Acoustic Neuroma Astrocytoma Biopsy Brain Metastasis Brain Tumor And Brain Cancer Brain, Spine Tumors Computer Guided Crainiotomy Craniotomy Epilepsy Glioblastoma Multiforme Meningioma Pituitary Adenoma Stereotactic Radiosurgery Multi-Disciplinary Training Area Developmental and Stem Cell Biology [DSCB] Education MD, University of Turin Medical School Residency, Surgery, Univ. of California, San Francisco Residency, Neurosurgery, Univ. of California, San Francisco Residency, Neurosurgery, Albert Einstein College of Medicine

Research Interest

Anti-Tumor Therapy, Apoptosis/Cell Death, Autophagy, Brain, Cancer, Cellular Differentiation, Gene Expressions, Gene Therapy, Metastasis, Migration, Molecular Biology, Neuroscience, Seizure, Stem Cells, Translation, Tumor Suppressor Genes, Tumorigenesis

Publications

  • Uzzaman M, Keller G, Germano I (2008) In vivo Gene Delivery by embryonic stem cell-derived astrocytes for malignant gliomas. Neuro-Oncology 11: 102-108.

  • Germano IM, Uzzaman M, Keller G (2008) Gene delivery by embryonic stem cells for malignant gliomas. Cancer Biology and Therapy 7: 1341-1347.

  • Benzil D, Abosch A, Germano IM, Gilmer H, Maraire N, etal (2008) The future of neurosurgery: a white paper on the recruitment and retention of women in neurosurgery. J Neurosurgery 109: 378-386.

  • Uzzaman M, Keller G, Germano IM (2009) In vivo Gene Delivery by embryonic stem cell-derived astrocytes for malignant gliomas. Neuro-Oncology 11: 102-108.

  • Uzzaman M, Keller G, Germano IM (2009) In vivo Gene Delivery by embryonic stem cell-derived astrocytes for malignant gliomas. Neuro-Oncology 11: 102-108.

  • Germano IM, Binello E (2009) Gene therapy as an adjuvant treatment of malignant gliomas: from bench to bedside. J Neuro-Oncology 93: 79-87.

  • Binello E, Germano IM (2009) Tonsillary carcinoma after temozolomide treatment for glioblastoma multiforme: treatment-related or dual-pathology?. J Neurooncol 94: 145-148.

  • Videtic GM, Gaspar LE, Aref AM, Germano IM, Goldsmith BJ, etal (2009) American College of Radiology Appropriateness Criteria┬« topic, Multiple Brain Metastases. J Radiation Oncology Biology Physics 75: 961-965.

  • Roberts CC, Daffner RH, Weissman BN, Bancroft L, Bennett DL, etal (2010) ACR appropriateness criteria on metastatic bone disease. J Am Coll Radiol 7: 400-409.

  • Germano IM, Emdad L, Qadeer ZA, Binello E, Uzzaman M (2010) Embryonic stem cell (ESC)-mediated transgene delivery induces growth suppression, apoptosis and radiosensitization, and overcomes temozolomide resistance in malignant gliomas.. Cancer Gene Ther.

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