James J Manfredi
Professor
Oncological Sciences,Cell, Developmental & Regenerative Biol
Icahn School of Medicine at Mount Sinai
United States of America
Biography
James j Manfredi at present is professor in the field of Oncological Science at ICAHN school of medicine, Mount Sinai.His Multi-Disciplinary Training Areas includes Biophysics and Systems Pharmacology [BSP], Cancer Biology [CAB], Genetics and Genomic Sciences [GGS]. His Education, MS from Albert Einstein College of Medicine and PhD from Albert Einstein College of Medicine.
Research Interest
Apoptosis/Cell Death, Cancer, Cell Cycle, Cell Division, Gene Regulation, Metastasis, Mitosis, Molecular Epidemiology, Nucleus, Oncogenes, Phosphorylation, Prostate, Protein Structure/Function, Transcription Factors, Transcriptional Activation and Repression, Viruses and Virology
Publications
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Giono LE, Manfredi JJ (2007) Mdm2 is required for inhibition of Cdk2 activity by p21, thereby contributing to p53-dependent cell cycle arrest. Molecular and cellular biology Vol: 27.
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Manfredi JJ, Dong J, Liu WJ, Resnick-Silverman L, Qiao R, etal (2005) Evidence against a role for SV40 in human mesothelioma. Cancer research Vol: 65.
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St. Clair S, Giono L, Varmeh-Ziaie S, Resnick-Silverman L, Liu WJ, etal (2004) DNA damage-induced downregulation of Cdc25C is mediated by p53 via two independent mechanisms: one involves direct binding to the cdc25C promoter. Mol Cell 16: 725-736.
