Nicole C Dubois
ASSISTANT PROFESSOR
ell, Developmental & Regenerative Biology
Icahn School of Medicine
United States of America
Biography
In the Dubois lab we are interested in understanding human heart development and disease. We are using the human pluripotent stem cell (hPSC) model to investigate the cellular and molecular mechanisms of cell fate specification and disease in the early human heart. For more detailed information please visit us on our lab website http://research.mssm.edu/duboislab/ Multi-Disciplinary Training Areas Biophysics and Systems Pharmacology [BSP], Developmental and Stem Cell Biology [DSCB] Education BA, Swiss Federal Institute of Technology Zurich (ETHZ) PhD, Swiss Institute for Experimental Cancer Research (ISREC) postdoc, McEwen Centre for Regenerative Medicine Toronto
Research Interest
Cardiovascular, Cellular Differentiation, Developmental Biology, Molecular Biology, Regeneration, Stem Cells
Publications
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Cashman TJ, Josowitz R, Gelb BD, Li RA, Dubois NC, etal (2016) Construction of Defined Human Engineered Cardiac Tissues to Study Mechanisms of Cardiac Cell Therapy. Journal of visualized experiments : JoVE.
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Zeltner N, Fattahi F, Dubois NC, Saurat N, Lafaille F,etal (2016) Capturing the biology of disease severity in a PSC-based model of familial dysautonomia. Nature medicine Vol: 22.
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Bardot E, Calderon D, Santoriello F, Han S, Cheung K, etal (2017) Foxa2 identifies a cardiac progenitor population with ventricular differentiation potential. Nature communications Vol: 8.