Diana Libuda
Assistant professor
Biology Member
Institute of Molecular Biology
United States of America
Biography
Diana Libuda is a Biology Member currently works as a Assistant professor in the Institute of Molecular Biology. Diana Libuda research interest are DNA repair, recombination, and chromosome dynamics during meiosis The Libuda Lab investigates how developing sperm and eggs repair DNA breaks with the proper chromosome template to ensure faithful genome inheritance from one generation to another.
Research Interest
DNA repair, recombination, and chromosome dynamics during meiosis
Publications
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Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development. Ivkovic S, Yoon BS, Popoff SN, Safadi FF, Libuda DE, Stephenson RC, Daluiski A, Lyons KM Development 2003 Jun;130(12):2779-91
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Amplification of histone genes by circular chromosome formation in Saccharomyces cerevisiae. Libuda DE, Winston F Nature 2006 Oct 26;443(7114):1003-7
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Alterations in DNA replication and histone levels promote histone gene amplification in Saccharomyces cerevisiae. Libuda DE, Winston F Genetics 2010 Apr;184(4):985-97
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Robust crossover assurance and regulated interhomolog access maintain meiotic crossover number. Rosu S, Libuda DE, Villeneuve AM Science 2011 Dec 2;334(6060):1286-9
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Meiotic chromosome structures constrain and respond to designation of crossover sites. Libuda DE, Uzawa S, Meyer BJ, Villeneuve AM Nature 2013 Oct 31;502(7473):703-6
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The C. elegans DSB-2 protein reveals a regulatory network that controls competence for meiotic DSB formation and promotes crossover assurance. Rosu S, Zawadzki KA, Stamper EL, Libuda DE, Reese AL, Dernburg AF, Villeneuve AM PLoS Genet 2013;9(8):e1003674
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DNA helicase HIM-6/BLM both promotes MutSγ-dependent crossovers and antagonizes MutSγ-independent interhomolog associations during caenorhabditis elegans meiosis. Schvarzstein M, Pattabiraman D, Libuda DE, Ramadugu A, Tam A, Martinez-Perez E, Roelens B, Zawadzki KA, Yokoo R, Rosu S, Severson AF, Meyer BJ, Nabeshima K, Villeneuve AM Genetics 2014 Sep;198(1):193-207
