John D Altman, Phd
Faculty
Pathogens
International Vaccine Institute
United States of America
Biography
Our MHC tetramer technology has played an essential role in defining the distribution of T cell subsets specific for a variety of pathogens, and this continues to be a central focus of the work in our laboratory. We are interested in both defining the relationships between T cell phenotypes and effector functions that can be assessed using short-term in vitro assays (that do not require amplification of T cell populations), as well as using adoptive transfer experiments in mouse models that permit in vivo testing of the efficacy of purified T cell subsets.
Research Interest
specific for a variety of pathogens, and this continues to be a central focus of the work in our laboratory. We are interested in both defining the relationships between T cell phenotypes and effector functions that can be assessed using short-term in vitro assays
