Abiche Dewilde

Biography

Abiche H Dewilde, Ph.D, received her Bachelors of Science from Worcester Polytechnic Institute in Biotechnology, her Masters in Science from the University of Massachusetts Lowell in Biology and Biotechnology and her Ph.D. from University of Massachusetts in Biomedical Engineering and Biotechnology. She conducted her postdoctoral fellowships in radiation mitigation biology and biosensor development at University of Massachusetts Lowell. Abiche has conducted research on multiple grants on tissue and limb regeneration, cancer treatment using nanoparticle conjugated targeted therapies, nanotoxicology research and cancer research using the Quartz Crystal Microbalance (QCM). Abiche’s doctoral dissertation research involved developing the QCM as a whole cell biosensor for the detection of toxins and other physiological changes within the cell. She successfully developed the cell based QCM biosensor to measure nanotoxicity of different nanomaterials as well as toxins like sodium azide. She published a first author paper showing for the first time that QCM can sense subcellular organelles. During Abiche’s postdoctoral fellowship she developed in conjunction with Berk Akinci a multi-well cell-based QCM Biosensor for phenotypic cell drug discovery, toxicity testing and cancer diagnosis. During this time, with the team, Abiche filed a patent for multi-well quartz crystal microbalance mass and viscoelastic sensor. She also conducted research into mitigators of radiation induced lung pneumonitis in in vivo models using gamma and neutron radiation at the UMass Lowell research nuclear reactor. 

Research Interest

Providing pharmaceutical and research industry with a multi-well whole-cell biosensor. Enabling quantitative measurement of phenotypic changes in drug discovery.