Biochemistry Experts

Roger Mcmacken

Biochemistry and Molecular Biology
Johns Hopkins Bloomberg School of Public Health
United States of America


Dr. Roger McMacken is currently affiliated to Johns Hopkins Bloomberg School of Public Health, United States of America, continuing research in the specialized scientific area of Bio-Chemistry and Molecular Biology. Education: PhD, University of Wisconsin, 1970

Research Interest

Biochemistry and molecular biology biochemical mechanisms DNA replication macromolecular assemblies DNA supercoiling DNA helicases protein-DNA interactions protein structure and function molecular chaperones heat shock proteins remodeling of protein assemblies


  • Leng, F. and McMacken, R. (2002). Potent stimulation of transcription-coupled DNA supercoiling by sequence-specific DNA-binding proteins. Proc. Natl. Acad. Sci. USA 99:9139-9144.

  • Leng, F. , Amado, L., and McMacken, R. (2003). Coupling DNA supercoiling to transcription in defined protein systems. J. Biol. Chem. 279:47564-47571.

  • Struble, E.B., Gittis, A.G., Bianchet, M.A., and McMacken, R. (2007) Crystallization and Preliminary Crystallographic Characterization of the Origin-binding Domain of the Bacteriophage Lambda O Replication Initiator. Acta Cryst. F63:542-545.

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