Pathology
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Pathology Experts

Angelo Michael Demarzo

Professor
Pathology
Johns Hopkins University
United States of America

Biography

Dr. Angelo De Marzo is a professor of pathology, oncology and urology at the Johns Hopkins University School of Medicine. His areas of clinical expertise include pathology and prostate cancer. Dr. De Marzo serves as the associate director of Cancer Research Pathology at the Sidney Kimmel Comprehensive Cancer Center. Dr. De Marzo founded the Tissue Microarray Core at Johns Hopkins, now known as the Oncology Tissue Services. He led it for a decade and now serves as an advisor to the core. Dr. De Marzo's research interests include the molecular pathobiology of prostate cancer, biospecimen banking, biomarker development and tissue microarrays. Dr. De Marzo received his B.A. in molecular, cellular and developmental biology and psychology from the University of Colorado at Boulder. He earned his M.D. and Ph.D. in experimental pathology from University of Colorado Health Sciences Center. He completed his residency in pathology at the Johns Hopkins School of Medicine and performed a fellowship at the Brady Urological Institute at Johns Hopkins. Dr. De Marzo joined the Johns Hopkins faculty in 1998. Dr. De Marzo was Chief Medical Officer at Predictive Biosciences Inc. until 2013, and serves on the editorial boards of the journals, The Prostate and Cancer Prevention Research. He is the recipient of the 2004 Donald S. Coffey Prostate Cancer Foundation Physician/Scientist Award and is a member of various professional organizations, including the American Urological Association and the American Association for Cancer Research.

Research Interest

Tissue microarrays; Biomarker development; Biospecimen banking; MYC, PTEN and prostate cancer; Prostate cancer and inflammation

Publications

  • Haffner MC, Mosbruger T, Esopi DM, Fedor H, Heaphy CM, Walker DA, Adejola N, Gürel M, Hicks J, Meeker AK, Halushka MK, Simons JW, Isaacs WB, De Marzo AM, Nelson WG, Yegnasubramanian S. "Tracking the clonal origin of lethal prostate cancer." J Clin Invest. 2013 Nov 1;123(11):4918-22.

  • Hurwitz LM, Heaphy CM, Joshu CE, Isaacs WB, Konishi Y, De Marzo AM, Isaacs SD, Wiley KE, Platz EA, Meeker AK. "Telomere length as a risk factor for hereditary prostate cancer." Prostate. 2014 Apr;74(4):359-64.

  • Canene-Adams K, Sfanos KS, Liang CT, Yegnasubramanian S, Nelson WG, Brayton C, De Marzo AM. "Dietary Chemoprevention of PhIP Induced Carcinogenesis in Male Fischer 344 Rats with Tomato and Broccoli." PLoS One. 2013 Nov 27;8(11):e79842.

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