Kenneth Jay Cohen
Professor
Oncology
Johns Hopkins University
United States of America
Biography
Dr. Cohen is Director of Pediatric Neuro-Oncology and Clinical Director of the Division of Pediatric Oncology at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. He received his undergraduate degree at Brown University and earned his MD at the Upstate Medical University, in Syracuse, NY. He did his general Pediatric Residency and Chief Residency at the University of Colorado, and completed his Pediatric Hematology/Oncology Fellowship at Johns Hopkins. He has served on the faculty since 1994. Dr. Cohen is co-chair of the High-Grade Glioma committee for the Children's Oncology Group and in that capacity has a particular research interest in the development of therapeutics for the treatment of infiltrating gliomas. He is Chief Medical Officer and head of the Scientific Advisory Board for Solving Kids Cancer. He is a Scientific Advisor for the Childhood Brain Tumor Foundation. The Pediatric Neuro-Oncology program conducts a broad range of research centered primarily around the development and testing of novel therapeutics for children with brain tumors. Included in this research has been the use of low-dose, long-exposure treatment strategies as well as the selective use of high-dose treatment regimens. The multidisciplinary nature of this work translates into continual collaboration with specialists in pediatric neurosurgery, radiation oncology, neuropathology, neuroradiology, neurology, neuro-ophthalmology, and other related disciplines. Research is also coordinated with the Neuropsychology group at the Kennedy-Krieger Institute.
Research Interest
Small-molecule and biological regulatory mechanisms; Control of DNA replication and chromosome superstructure; Structural and catalytic mechanisms of nucleic-acid machines and assemblies
Publications
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Cohen KJ, Gibbs IC, Fisher PG, Hayashi RJ, Macy ME, Gore L. A phase I trial of arsenic trioxide chemoradiotherapy for infiltrating astrocytomas of childhood. Neuro Oncol. 2013 Mar 3.
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Cohen KJ, Heideman RL, Zhou T, Holmes EJ, Lavey RS, Bouffet E, Pollack IF. Temozolomide in the treatment of children with newly diagnosed diffuse intrinsic pontine gliomas: A report from the Children's Oncology Group. Neuro Oncol. 2011 Apr;13(4):410-6
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Cohen KJ, Pollack IF, Zhou T, Buxton A, Holmes EJ, Burger PC, Brat DJ, Rosenblum MK, Hamilton RL, Lavey RS, Heideman RL. Temozolomide in the treatment of high-grade gliomas in children; a report from the Children's Oncology Group. Neuro Oncol. 2011 Mar;13(3):317-23