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Subroto B. Chatterjee

Professor
Pediatrics
Johns Hopkins University
United States of America

Biography

Dr. Subroto Chatterjee is a professor of pediatrics at the Johns Hopkins University School of Medicine. He is an internationally recognized expert in glycolipids, atherosclerosis and vascular biology. His research team recently discovered how to halt the development of atherosclerotic heart disease in animals. Dr. Chatterjee serves as the director of the Sphingolipid Signaling and Vascular Biology Laboratory. His team is currently studying how glycosphinglipids in vascular cells regulate the onset of atherosclerosis and hypercholesterolemia. Dr. Chatterjee received his undergraduate degree in chemistry from Lucknow University in India. He earned his M.Sc. in biochemistry from Lucknow University, his M.S. in biochemistry from Dalhousie University in Canada, and his Ph.D. in biochemistry from the University of Toronto. He completed a post-doctoral fellowship in biochemistry at Michigan State University. Dr. Chatterjee joined the Johns Hopkins faculty in 1975. Prior to joining Johns Hopkins, Dr. Chatterjee was a research associate at Michigan State University. He served as the director of the Atherosclerosis and Vascular Biology Program at Johns Hopkins Singapore for five years. In addition to his research activities, Dr. Chatterjee teaches M.D. and Ph.D. candidates in the Cell and Molecular Medicine graduate program. He has published more than 250 peer-reviewed papers, review articles, and book chapters in the areas of glycosphingolipids, glycosyltransferases, atherosclerosis , lipoproteins and vascular biology. He has approximately 75 U.S. and worldwide patents for his discoveries and inventions, and has founded three biotechnology companies. Dr. Chatterjee serves on the scientific advisory board and as a thought leader to Merck. He is a member of several professional organizations, including the Federation of the American Society of Biological Chemists and the American Society for the Advancement of Science. Dr. Chatterjee has received numerous national and international awards for his service to the American heart Association. In addition, he received the Distinguished Scientist award from Gov. Parris Glendening of Maryland, the Mizutani Award and the Distinguished Medical Research Scientist Award from the Ranbaxy Science Foundation in 2004.

Research Interest

Drug discovery and biotechnology; Lipid and vascular biology translational research

Publications

  • Mishra S, Chatterjee S. "Lactosylceramide promotes hypertrophy through ROS generation and activation of ERK1/2 in cardiomyocytes." Glycobiology. 2014 Jun;24(6):518-31.

  • Chatterjee S, Bedja D, Mishra S, Amuzie C, Avolio A, Kass DA, Berkowitz D, Renehan M. "Inhibition of glycosphingolipid synthesis ameliorates atherosclerosis and arterial stiffness in apolipoprotein E-/- mice and rabbits fed a high-fat and -cholesterol diet." Circulation. 2014 Jun 10;129(23):2403-13.

  • Chatterjee S, Mishra S, Suzuki SK. "New vis-tas in lactosylceramide research." Adv Exp Med Biol. 2015;842:127-38.

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