Stuart J. Macdonald
Professor
Department of Chemistry
Kansas City University of Medicine and Biosciences
United States of America
Biography
Stuart Macdonald earned a B.A. in biological sciences (1997) and a D.Phil in zoology (2000) from the University of Oxford, was a postdoctoral researcher in the lab of Dr. Tony Long at the University of California - Irvine, and in 2006 started his faculty position in the Department of Molecular Biosciences at the University of Kansas. Dr. Macdonald is also an affiliate member of the Center for Computational Biology, the Director of the K-INBRE Bioinformatics Core at KU, and the Director of Graduate Studies for the Department of Molecular Biosciences. Research in the Macdonald lab focuses on understanding the genetic basis of complex trait variation, principally using Drosophila as a model system. The lab employs a range of genetic, genomic, bioinformatic and functional tools to identify genes and sequence variants controlling trait variation. In addition, the Macdonald lab leads the development of a large, powerful set of resources for the dissection of trait variation in flies, the Drosophila Synthetic Population Resource (DSPR).
Research Interest
Molecular Biosciences
Publications
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Cloud-Richardson, K. M, Smith, B. R, & Macdonald, S. J (2016). Genetic dissection of intraspecific variation in a male-specific sexual trait in Drosophila melanogaster. Heredity, 117(6), 417-426. DOI:10.1038/hdy.2016.63 Najarro, M. A, Hackett, J. L, Smith, B. R, Highfill, C. A, King, E. G, Long, A. D, & Macdonald, S. J (2015). Identifying Loci Contributing to Natural Variation in Xenobiotic Resistance in Drosophila. PLoS genetics, 11(11), e1005663. DOI:10.1371/journal.pgen.1005663 Marriage, T. N, King, E. G, Long, A. D, & Macdonald, S. J (2014). Fine-mapping nicotine resistance Loci in Drosophila using a multiparent advanced generation inter-cross population. Genetics, 198(1), 45-57. DOI:10.1534/genetics.114.162107
