Hooman Allayee
ProfessorÂÂ
Preventive Medicine
Keck School of Medicine
United States of America
Biography
Dr. Allayee is Professor of Preventive Medicine and Biochemistry & Molecular Medicine at the Keck School of Medicine of USC. His research program is focused on using multi-disciplinary genetics/genomics approaches to understand complex disorders, with an emphasis on cardiovascular, metabolic, and inflammatory diseases. In particular, his laboratory employs systems genetics strategies to dissect the architecture of complex diseases where a variety of intermediate phenotypes at the molecular, proteomic, and metabolomic levels are integrated into the genetic analyses. Current projects involve large-scale population studies in humans, gene-environment interactions, functional experiments using molecular genetics techniques, and the generation and characterization of mouse models. Dr. Allayee received his Ph.D. in Microbiology and Molecular Genetics in 1999 from the University of California, Los Angeles. Prior to joining USC, Dr. Allayee completed NIH Postdoctoral Fellowships at Harbor-UCLA Medical Center and the David Geffen School of Medicine UCLA.
Research Interest
cardiovascular, metabolic, and inflammatory diseases.
Publications
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Lavinsky J, Ge M, Crow AL, Pan C, Wang J, Salehi P, Myint A, Eskin E, Allayee H, Lusis AJ, Friedman RA. The Genetic Architecture of Noise-Induced Hearing Loss: Evidence for a Gene-by-Environment Interaction. G3 (Bethesda). 2016 Oct 13;6(10):3219-3228.
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Trumble BC, Stieglitz J, Blackwell AD, Allayee H, Beheim B, Finch CE, Gurven M, Kaplan H. Apolipoprotein E4 is associated with improved cognitive function in Amazonian forager-horticulturalists with a high parasite burden. FASEB J. 2017 Apr;31(4):1508-1515.
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Hartiala J, Schwartzman WS, Gabbay J, Ghazalpour A, Bennett BJ, Allayee H. The Genetic Architecture of Coronary Artery Disease: Current Knowledge and Future Opportunities. Curr Atheroscler Rep. 2017 Feb;19(2):6.
