Marcel E Nimni
ProfessorÂÂ
Biochemistry and Molecular Medicine
Keck School of Medicine
United States of America
Biography
Dr. Nimni is a Professor of Surgery, Biochemistry & Molecular Biology and Biomedical Engineering, and Director of Tissue Engineering Laboratories at the Keck School of Medicine of USC. His major areas of research activities include: Biochemistry of collagen: molecular structure, biosynthesis, mechanisms of crosslinking in soft tissues, bone and cartilage; interactions between connective tissues constituents, biochemical changes in degenerative diseases. Cell culture. Hydrophobic interactions involved in the self-assembly of macromolecules. Biochemistry of vascular tissues. Trans-dermal drug delivery. Mechanism of bone formation and dystrophic calcification. Osteogenesis: decline of osteoprogenitor cells with age. Collagen derived bioprosthesis. Growth factors (TGF-B, BMP’s and others). Bone and cartilage repair. Sulfur amino acids and glutathione: relationship to tissue repair.
Research Interest
Surgery, Biochemistry & Molecular Biology and Biomedical Engineering
Publications
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Hoang BX, Han B, Shaw DG, Nimni M. Zinc as a possible preventive and therapeutic agent in pancreatic, prostate, and breast cancer. European Journal of Cancer Prevention. 2016 Sep 1;25(5):457-61.
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Hoang BX, Shaw DG, Han B, Fang JY, Nimni M. Acidosis and Formaldehyde Secretion as a Possible Pathway of Cancer Pain and Options for Improved Cancer Pain Control. Journal of pain & palliative care pharmacotherapy. 2015 Jul 3;29(3):276-80.