Chuan Wu
NIH Stadtman Investigator
Experimental Immunology
Laboratory of Cell and Molecular Biology
United States of America
Biography
Dr. Wu completed his M.D. studies in China at Shanghai Jiaotong University School of Medicine, and then studied immunology and matrix biology as a graduate student at Muenster University, Germany. His main focus was T cell migration during the central nervous system (CNS) inflammation. He joined Dr. Vijay Kuchroo’s lab in Brigham and Women’s Hospital, Harvard Medical School as a postdoctoral fellow where he studied the molecular regulation of T cell differentiation during inflammation and autoimmunity. In 2017, Dr. Wu started a position as an NIH Stadtman Tenure-Track Investigator at the Experimental Immunology Branch where he studies the cellular and molecular mechanisms of neuro-immune interactions.
Research Interest
T cell differentiation and function, Inflammation, Neuron-immune interaction, Mucosal immune response
Publications
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Wu C, Yosef N, Thalhamer T, Zhu C, Xiao S, Kishi Y, Regev A, Kuchroo V. Induction of pathogenic Th17 cells by inducible salt sensing kinase SGK1. Nature. 2013 Apr 25;496(7446):513.
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Wu C, Pot C, Apetoh L, Thalhamer T, Zhu B, Murugaiyan G, Xiao S, Lee Y, Rangachari M, Yosef N, Kuchroo VK. Metallothioneins negatively regulate IL-27–induced type 1 regulatory T-cell differentiation. Proceedings of the National Academy of Sciences. 2013 May 7;110(19):7802-7.
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Wu C, Chen Z, Dardalhon V, Xiao S, Thalhamer T, Liao M, Madi A, Franca RF, Han T, Oukka M, Kuchroo V. The transcription factor musculin promotes the unidirectional development of peripheral Treg cells by suppressing the TH2 transcriptional program. Nature immunology. 2017 Mar 1;18(3):344-53.
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Wu C, Chen Z, Dardalhon V, Xiao S, Thalhamer T, Liao M, Madi A, Franca RF, Han T, Oukka M, Kuchroo V. The transcription factor musculin promotes the unidirectional development of peripheral Treg cells by suppressing the TH2 transcriptional program. Nature immunology. 2017 Mar 1;18(3):344-53.
