Paul A. Randazzo
Senior Investigator
Cellular and Molecular Biology
Laboratory of Cell and Molecular Biology
United States of America
Biography
Paul Randazzo received his M.D. and Ph.D. from Brown University. He received residency training in anatomic pathology at the Hospital of the University of Pennsylvania, predoctoral training in the laboratory of John N. Fain and postdoctoral training in the laboratory of Richard A. Kahn.
Research Interest
Ras-superfamily Guanine Nucleotide Binding Proteins, ADP-ribosylation factor Guanine Nucleotide Binding Proteins, GTPase-activating proteins (GAPs)
Publications
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Chen PW, Jian X, Luo R, Randazzo PA. Approaches to studying Arf GAPs in cells: in vitro assay with isolated focal adhesions. Current protocols in cell biology. 2012 Jun 20:17-3.
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The N-terminus of a-subunit isoforms is involved in signaling between vacuolar H+-ATPase (V-ATPase) and cytohesin-2
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Chen PW, Jian X, Yoon HY, Randazzo PA. ARAP2 signals through Arf6 and Rac1 to control focal adhesion morphology. Journal of Biological Chemistry. 2013 Feb 22;288(8):5849-60.
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Shiba Y, Kametaka S, Waguri S, Presley JF, Randazzo PA. ArfGAP3 regulates the transport of cation-independent mannose 6-phosphate receptor in the post-Golgi compartment. Current Biology. 2013 Oct 7;23(19):1945-51.
