Valarie A. Barr
Cellular and Molecular Biology
Scientist
Laboratory of Cell and Molecular Biology
United States of America
Biography
Dr. Barr obtained her Bachelor and Master of Science degrees from the University of Illinois. She completed her graduate work at The Johns Hopkins University, Department of Cell Biology and Anatomy and obtained a Ph.D in cell biology in 1994. After a postdoctoral fellowship in the laboratory of Dr. Simean Taylor at the Diabetes Branch in the National Institute of Diabetes, Digestive and Kidney Diseases, Dr. Barr joined the Laboratory of Cellular and Molecular Biology in the National Cancer Institute in 2001.
Research Interest
Localization microscopy, TIRF microscopy, Confocal microscopy, Live cell imaging
Publications
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Sherman E, Barr VA, Samelson LE. Resolving multi-molecular protein interactions by photoactivated localization microscopy. Methods. 2013 Mar 1;59(3):261-9.
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Coussens NP, Hayashi R, Brown PH, Balagopalan L, Balbo A, Akpan I, Houtman JC, Barr VA, Schuck P, Appella E, Samelson LE. Multipoint binding of the SLP-76 SH2 domain to ADAP is critical for oligomerization of SLP-76 signaling complexes in stimulated T cells. Molecular and cellular biology. 2013 Nov 1;33(21):4140-51.
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Balagopalan L, Barr VA, Kortum RL, Park AK, Samelson LE. Cutting edge: cell surface linker for activation of T cells is recruited to microclusters and is active in signaling. The Journal of Immunology. 2013 Apr 15;190(8):3849-53.
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Zvezdova E, Lee J, El-Khoury D, Barr V, Akpan I, Samelson L, Love PE. In vivo functional mapping of the conserved protein domains within murine Themis1. Immunology and cell biology. 2014 Sep;92(8):721.