Ying E. Zhang
Senior Investigator
Cellular and Molecular Biology
Laboratory of Cell and Molecular Biology
United States of America
Biography
Dr. Ying Zhang received her B.S. degree in Chemistry and M.S. degree in Biochemistry from Peking University, China. She obtained her Ph.D. degree from University of Wisconsin-Madison in 1995 and completed her postdoctoral training with Dr. Rik Derynck in University of California, San Francisco. She joined the Laboratory of Cellular and Molecular Biology in 2000 as a tenure-track investigator and became a senior investigator in 2007.
Research Interest
Signaling Transduction, TGF-beta signaling, Protein kinases, Ubiquitination, Mouse models, Metastasis
Publications
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Yang YA, Zhang GM, Feigenbaum L, Zhang YE. Smad3 reduces susceptibility to hepatocarcinoma by sensitizing hepatocytes to apoptosis through downregulation of Bcl-2. Cancer cell. 2006 Jun 13;9(6):445-57.
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Yamashita M, Fatyol K, Jin C, Wang X, Liu Z, Zhang YE. TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-β. Molecular cell. 2008 Sep 26;31(6):918-24.
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Blank M, Tang Y, Yamashita M, Burkett SS, Cheng SY, Zhang YE. A tumor suppressor function of Smurf2 associated with controlling chromatin landscape and genome stability through RNF20. Nature medicine. 2012 Feb 1;18(2):227-34.
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Tripathi V, Sixt KM, Gao S, Xu X, Huang J, Weigert R, Zhou M, Zhang YE. Direct regulation of alternative splicing by SMAD3 through PCBP1 is essential to the tumor-promoting role of TGF-β. Molecular cell. 2016 Nov 3;64(3):549-64.
