Christopher G. Wilson
Associate Professor
Division of Physiology
Loma Linda University
United States of America
Biography
Dr. Christopher G. Wilson is currently working as a Associate Professor in the Department of Division of Physiology, Loma Linda University , U.S.A. His research interests includes the generation and modulation of respiratory rhythm in the mammalian central nervous system. He is serving as an editorial member and reviewer of several international reputed journals. Dr. Christopher G. Wilson is the member of many international affiliations. He has successfully completed his Administrative responsibilities. He has authored of many research articles/books related to the generation and modulation of respiratory rhythm in the mammalian central nervous system.
Research Interest
My laboratory is primarily interested in the generation and modulation of respiratory rhythm in the mammalian central nervous system. In the past decade, we have focused on apnea of prematurity and other breathing problems that premature infants suffer. The questions we seek to answer are: How does the brain generate the drive for breathing? How is breathing pattern modulated by reflexes and chemosensation? How can we improve breathing regularity in premature infants? We use electrophysiology techniques (extracellular single-unit recording, whole cell patch-clamp, electrochemistry) and fluorescence imaging (calcium indicators, pH sensitive dyes, cell specific markers) to explore the dynamic relationship between cells that are phasically active during breathing. Our chief animal model is the developing rat but we also use mice to explore genetic variability in the respiratory neural substrate.
Publications
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Diekman CO, Wilson CG, Thomas PJ. Spontaneous autoresuscitation in a model of respiratory control. Conf Proc IEEE Eng Med Biol Soc. 2012;2012:6669-72. doi: 10.1109/EMBC.2012.6347524. PMID: 23367459
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Jafri A, Belkadi A, Zaidi SI, Getsy P, Wilson CG, Martin RJ. Lung inflammation induces IL-1β expression in hypoglossal neurons in rat brainstem. Respir Physiol Neurobiol. 2013 Aug 1;188(1):21-8. doi: 10.1016/j.resp.2013.04.022. Epub 2013 May 3. PMID: 23648475
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Martin RJ, Wilson CG. Apnea of prematurity. Compr Physiol. 2012 Oct;2(4):2923-31. doi: 10.1002/cphy.c100021. PMID: 23720269