David Hessinger
Professor
Division of Physiology
Loma Linda University
United States of America
Biography
Dr. David Hessinger is currently working as a Professor in the Department of Division of Physiology, Loma Linda University , U.S.A. His research interests includes regulation and function of ion channels in vascular smooth muscle and satiety/obesity. . He is serving as an editorial member and reviewer of several international reputed journals. Dr. David Hessinger is the member of many international affiliations. He has successfully completed his Administrative responsibilities. He has authored of many research articles/books related to regulation and function of ion channels in vascular smooth muscle and satiety/obesity. .
Research Interest
Our research focuses on regulation and function of ion channels in vascular smooth muscle and satiety/obesity. In vascular physiology, we currently use a sheep model to study the role of large-conductance potassium (BK) channels in (i) pulmonary vasodilation at birth and (ii) adult and fetal cerebral artery high-altitude acclimatization. In satiety physiology, we use en-masse cultured, monoclonal sea anemones to identify and study conserved pathways involved in satiety regulation.
Publications
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Thorington, Glyne U. and Hessinger, David A. Roles of calcium in nematocyst discharge from sea anemone (Aiptasia pallida and Haliplanella luciae) tentacles. J Exp Biol, manuscript #JEXBIO/078329, accepted with revisions.
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Tao, Xiaoxiao, Shi, Lijun, Longo, Lawrence D., Hessinger, Lawrence D. Protein Kinase C activates BK channels in fetal, but not adult, middle cerebral arteries. Submitted to Am J Physiol, Regulatory, Integrative, Comp Physiol; manuscript no. R-00352-2014.
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Tao, Xiaoxiao, Lin, Mike T., Thorington, Glyne U., Wilson, Sean M., Longo, Lawrence D., Hessinger, David A. Long-Term Hypoxia Increases Calcium Affinity of BK Channels in Ovine Fetal and Adult Cerebral Artery Smooth Muscle. Am J Physiol, Heart Circ; manuscript no. H-005644-2014.