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Oncology Experts

Eun-jung Park

Research Scientist
Cancer Research Laboratories
Long Island University
United States of America

Biography

Dr. Eun-Jung Park earned her Ph.D. in pharmacognosy from Ewha Womans University, with a dissertation entitled “cancer chemopreventive potential of natural product-derived stilbenoids in multistage carcinogenesis”. Dr. Park evaluated the activities of natural products and their analogs on three stages of carcinogenesis, including initiation, promotion and progression, using in vitro cell line based assay. Upon active compounds, Dr. Park studied further to elucidate the molecular mechanisms. She received a Scholar-in-training Award from American Association for Cancer Research (AACR) with her work in 2006. Since then, she is an associate member of AACR. After graduation, Dr. Park joined University of Hawaii as a postdoctoral fellow, and continued her career as a research specialist at the The Daniel K. Inouye College of Pharmacy, University of Hawai’i at Hilo, HI. During this period, she examined the effects of a multitude of samples on nitrite production, aromatase enzymatic activity, free radical production, cancer cell proliferation, transcriptional activity of retinoid X receptor, etc. Various compounds or extracts were found as active, including marine macro- and microorganisms, norsesterterpene peroxides, resveratrol analogs, phenolic glycosides, phenazines, isothiocyanate derivatives, callophycin A analogs, thiadiazole analogs, indenoisoquinolines, sesquiterpene lactones, 2-arylindole derivatives, withanolides, and azaphilones. In 2016, Dr. Park joined College of Pharmacy and Health Sciences, Long Island University as a research scientist. Her current research is focused on the effect of grape-containing diets (regular diet and Western diet) on health and longevity.

Research Interest

Pharmacognosy,nitrite production, aromatase enzymatic activity, free radical production, cancer cell proliferation, transcriptional activity of retinoid X receptor, etc

Publications

  • Inhibitory effect of a callophycin A derivative on iNOS expression via inhibition of Akt in lipopolysaccharide-stimulated RAW 264.7 cells. J Nat Prod. 2014

  • The pharmacology of resveratrol in animals and humans. Biochim Biophys Acta. 2015

  • Induction of cell cycle arrest and apoptosis with downregulation of Hsp90 client proteins and histone modification by 4β-hydroxywithanolide E isolated from Physalis peruviana. Mol Nutr Food Res. 2016

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