Samuel W French
Los Angeles Biomedical Research Institute
United States of America
Dr. French is a renowned expert in pathology of the liver and one of the pioneers in establishing the nature of the liver cell cytoskeleton and the pathogenesis of Mallory bodies. His research includes the pathogenesis of alcoholic and liver disease, more specifically investigating the regulation of expression of RNA sequence genes in liver biopsies from patients with acute alcoholic hepatitis.
Pathology of the liver,pathogenesis of Mallory bodies
Alcoholic steatohepatitis (ASH) causes more UPR-ER stress than non-alcoholic steatohepatitis (NASH). Exp Mol Pathol. 2016
Alcohol, microbiome, life style influence alcohol and non-alcoholic organ damage. Exp Mol Pathol. 2017
Over expression of proteins that alter the intracellular signaling pathways in the cytoplasm of the liver cells forming Mallory-Denk bodies. Exp Mol Pathol. 2017