Biomedical Sciences

Biomedical Sciences Experts

Iasemidis, Leonidas

Biomedical Engineering
Louisiana Tech University
United States of America


Dr. Iasemidis is a world renowned expert in nonlinear dynamics and the development of new measures of dynamics for the detection, prediction and control of crises in complex coupled systems, in particular the animal and human epileptic brain. His research and over 100 peer-reviewed publications, interdisciplinary conference organizations, presentations and invited talks have stimulated an international interest in the prediction and control of epileptic seizures and understanding of the mechanisms of epileptogenesis. He is considered one of the founders of the field of seizure prediction and has collaborated with Mayo Clinic, Cleveland Clinic and the Barrow Neurological Institute. Dr. Iasemidis served on the editorial board of Epilepsia, the IEEE Transactions on Biomedical Engineering and the International Journal of Neural Systems, and currently is on the editorial board of the Annals of Biomedical Engineering and Epilepsy Research. He is a reviewer for a score of journals and research sponsoring national and international agencies, including the National Institutes of Health (NIH) and the National Science Foundation (NSF). Over the years, Dr. Iasemidis’ research has been funded by NIH, VA, DARPA, NSF, DoD, the Epilepsy Foundation of America, the Science Foundation of Arizona, the Whitaker Foundation and industry. He has co-founded three companies in the area of neuromodulation and control of epilepsy and is the co-author of 4 awarded, 2 pending and 9 provisional patents in these areas. His research has been highlighted on multiple forums, including the New York Times, Discover magazine, the Teaching Company, and the American Association for the Advancement of Science (AAAS). Dr. Iasemidis is currently an endowed Professor and the Rhodes Eminent Scholar Chair in the Biomedical Engineering Program, a Fellow of the American Institute of Medical and Biological Engineers (AIMBE), a Fellow of the National Academy of Inventors, the Director of the Center for Biomedical Engineering and Rehabilitation Science (CBERS) and the Director of the Brain Dynamics Laboratory at the College of Engineering and Science, Louisiana Tech University, Ruston, Louisiana, USA.

Research Interest

Design and implement novel methodology and advanced signal processing techniques to monitor, process and model the electrical and magnetic activity recorded from the brain for the purpose of diagnosis, differential diagnosis, evaluation of treatment, timely warning and intervention to avert catastrophic state transitions like epileptic seizures. The secondary goal is to interface the developed products with existing devices in biomedical industry used for monitoring and real-time treatment of the respective disorders, diseases and emergencies, for example, vagus nerve stimulators (VNS), deep brain stimulators (DBS), transcranial magnetic stimulators (TMS) and/or other neuromodulation devices based on timely in situ cooling of the brain or in situ administration of medication.


  • Scn2a deletion improves survival and brain–heart dynamics in the Kcna1-null mouse model of sudden unexpected death in epilepsy (SUDEP) V Mishra, BK Karumuri, NM Gautier, R Liu, TN Hutson, ... Human Molecular Genetics 26 (11), 2091-2103

  • System and method for identifying a focal area of abnormal network interactions in the brain LD Iasemidis, I Vlachos, B Krishnan, A Alexopoulos US Patent 9,730,628

  • The Concept of Effective Inflow: Application to Interictal Localization of the Epileptogenic Focus From iEEG I Vlachos, B Krishnan, DM Treiman, K Tsakalis, D Kugiumtzis, ... IEEE Transactions on Biomedical Engineering 64 (9), 2241-2252

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