Drena Dobbs
University Professor
Genetics, Development and Cell Biology
Lowa State University
United States of America
Biography
Professor Dobbs received her B.S. in Biology from the University of Georgia in 1977 and her Ph.D. in Molecular Biology from the University of Oregon in 1983. She received an NIH Postdoctoral Fellowship in 1984, and worked with Elizabeth Blackburn at the University of California, Berkeley. Dr. Dobbs joined Iowa State University in 1987. From 1999 through 2001, she served as the first Chair of the Bioinformatics and Computational Biology (BCB) Graduate Program at ISU. In 2015, Dr. Dobbs was named University Professor of Lowa State University.
Research Interest
Development of novel antiviral therapies against HIV-1 and other lentiviruses, Rational design of zinc finger proteins (ZFPs) as tools for genomic modification and gene therapy, Prediction of epitopes and nucleic acid binding residues in proteins, and prediction and experimental validation of structural and functional effects of mutations and SNPs in proteins.
Publications
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Muppirala UK, Lewis BA, Dobbs D (2013) Computational tools for investigating RNA-protein interaction partners. J Comput Sci Syst Biol 6: 182-187
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Xue LC, Jordan RA, El-Manzalawy Y, Dobbs D, Honavar V (2014) DockRank: ranking docked conformations using partner-specific sequence homology-based protein interface prediction. Proteins 82: 250-267.
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Andorf CM, Kopylov M, Dobbs D, Koch KE, Stroupe ME, et al. (2014) G-quadruplex (G4) motifs in the maize (Zea mays L.) genome are enriched at specific locations in thousands of genes coupled to energy status, hypoxia, low sugar, and nutrient deprivation. J Genet Genomics 41: 627-647.
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Dobbs D, Brenner SE, Honavar VG, Jernigan RL, Laederach A, et al. (2016) Regulatory RNA. Pac Symp Biocomput 21: 429-432.
