Jesse M Hostetter

Biography

Jesse M Hostetter is a Professor of Veterinary Pathology in Lowa State University.

Research Interest

Dr. Hostetter’s research interest is primarily in host-pathogen interaction, specifically between antigen presenting cells and intracellular pathogens. His research group’s focus is in atypical mycobacterial infections and the model organism is Mycobacterium avium subspecies paratuberculosis (MAP). Ongoing studies include evaluation of the roles of antigen presenting cells and gamma delta T cells in controlling pathogen proliferation, stimulation of adaptive immune responses, and shaping lesion development. Investigations also include evaluation of MAP infection in promoting persistent intestinal inflammation in the mouse. Studies utilize a wide array of techniques including in vivo and in vitro systems, smart polymers, flow cytometry, laser capture microdissection, Q-RT-PCR, SDS PAGE electrophoresis, and immunofluorescence. Multiple collaborations support these projects and include investigators at Iowa State University, University of Iowa, and the National Animal Disease Center. Dr. Hostetter is also the study pathologist on several studies exploring intestinal inflammation in murine models of colitis in collaboration with the Mucosal Immunology Laboratory at the College of Veterinary Medicine.