Ilyas Chachoua
Scientist
Ludwig Center at Brussels
Ludwig Institute for Cancer Research
United States of America
Biography
I am interested in determining the chromatin and transcriptional effects of constitutive STAT activation in myeloid cancers, cross-talk with p53 and epigenetic regulators, and in the mechanisms by which G-CSF receptor regulates hematopoiesis and contributes to leukemia.
Research Interest
Biochemistry, leukemia, myeloid cancers, epigenetic regulators
Publications
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Feenstra, Jelena D. Milosevic, et al. "Whole-exome sequencing identifies novel MPL and JAK2 mutations in triple-negative myeloproliferative neoplasms." Blood 127.3 (2016): 325-332.
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Marty, Caroline, et al. "Calreticulin mutants in mice induce an MPL-dependent thrombocytosis with frequent progression to myelofibrosis." Blood 127.10 (2016): 1317-1324.
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Chachoua, Ilyas, et al. "Thrombopoietin receptor activation by myeloproliferative neoplasm associated calreticulin mutants." Blood (2015): blood-2015.
