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Oncology Experts

Jean-christophe Renauld

Scientist
Ludwig Center at Brussels
Ludwig Institute for Cancer Research
United States of America

Biography

My research is focused on the characterization of cytokine activities using a multidisciplinary approach extending from molecular characterization of signal transduction and gene regulation pathways to in vivo studies of inflammatory and immune responses in transgenic and gene-targeted mice. We have a particular interest in the biology of Interleukin-9 (IL-9) and IL-22, two cytokines discovered in our lab. In addition to my Ludwig research activities, I am a Professor at the University of Louvain Medical School, where I am teaching Immunology and Cell Biology. I am serving on different national and international scientific committees and Editorial boards and I am a member of the Belgian Royal Academy of Medicine.

Research Interest

Gene regulation, cancer genetics, signalling, immunology

Publications

  • Dumoutier, Laure, et al. "Cutting edge: STAT activation by IL-19, IL-20 and mda-7 through IL-20 receptor complexes of two types." The Journal of Immunology 167.7 (2001): 3545-3549.

  • Dumoutier, Laure, Jamila Louahed, and Jean-Christophe Renauld. "Cloning and characterization of IL-10-related T cell-derived inducible factor (IL-TIF), a novel cytokine structurally related to IL-10 and inducible by IL-9." The Journal of Immunology 164.4 (2000): 1814-1819.

  • Veldhoen, Marc, et al. "The aryl hydrocarbon receptor links T^ sub H^ 17-cell-mediated autoimmunity to environmental toxins." Nature 453.7191 (2008): 106.

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