Jedd Wolchok
Scientist
Ludwig Center at MSKÂ
Ludwig Institute for Cancer Research
United States of America
Biography
My clinical experience has been focused on the development and investigation of novel immunotherapeutic approaches to the treatment of cancer. I initiated a program in xenogeneic DNA vaccination at Memorial Sloan-Kettering and followed the translational pathway from initial mouse studies through on-site GMP manufacturing to leading phase I trials. As part of this endeavor, in collaboration with Drs. Alan Houghton, James Allison and Lloyd Old, I helped to establish the Ludwig Center for Cancer Immunotherapy, which serves as the core facility for clinical immune monitoring at MSK.
Research Interest
Cancer, immunotherapy, clinical trials
Publications
-
Wolchok, Jedd D., et al. "Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria." Clinical cancer research 15.23 (2009): 7412-7420.
-
Robert, Caroline, et al. "Ipilimumab plus dacarbazine for previously untreated metastatic melanoma." New England Journal of Medicine 364.26 (2011): 2517-2526.
-
Hodi, F. Stephen, et al. "Improved survival with ipilimumab in patients with metastatic melanoma." N Engl j Med 2010.363 (2010): 711-723.
