Ludwig Center at MSK
Ludwig Institute for Cancer Research
United States of America
I received my BA degree from the University of Algiers, Algeria, and MS and PhD degrees with highest distinction from the University of Paris, France. My thesis findings provided insight to the correlation of genotypes and phenotypes in sickle cell anemia and thalassemia. I pursued my post-doctoral research with Dr. Pandolfi at Memorial Sloan-Kettering Cancer Center. He characterized the role of the Zbtb7 (Pokemon/LRF1) gene during development. I am an Associate Attending Biologist in the Melanoma Sarcoma Service and am an integral part of the Ludwig Collaborative and Swim Across America Laboratory. I co-direct the scientific direction and the projects being investigated. I mentor postdoctoral fellows, graduate students and technicians.
Melanoma, therapeutics, immunotherapy
Quezada, Sergio A., et al. "Tumor-reactive CD4+ T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts." Journal of Experimental Medicine 207.3 (2010): 637-650.
Snyder, Alexandra, et al. "Genetic basis for clinical response to CTLA-4 blockade in melanoma." New England Journal of Medicine 371.23 (2014): 2189-2199.
Rizvi, Naiyer A., et al. "Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer." Science 348.6230 (2015): 124-128.