Robert A. Weinberg
DIRECTOR
Ludwig Center at MIT
Massachusetts Institute of Technology
United States of America
Biography
I am Director of the Ludwig Center for Molecular Oncology at MIT, the Daniel K. Ludwig Professor for Cancer Research within MIT’s Department of Biology and a founding member of the Whitehead Institute for Biomedical Research. My co-workers and I isolated the first human cancer-causing gene, the ras oncogene, and the first known tumor suppressor gene, Rb, the retinoblastoma gene.
Research Interest
Tumor biology, cancer genomics,
Publications
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Guo, W., Keckesova, Z., Liu Donaher, J., Shibue, T., Tischler, V., Reinhardt, F., Itzkovitz, S., Noske, A., Zürrer-Härdi, U., Bell, G., Tam, W.L., Mani, S.A., van Oudenaarden, A., and Weinberg, R.A. (2011). Slug and Sox9 Cooperatively Determine the Mammary Stem Cell State. Cell 148:1015-1028.
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Scheel, C., Chaffer, C.L,. Eaton, E. N., Hsin-Jung, L., Kah, K.J., Birie, B., Reinhardt, F., and Weinberg, R.A. An autocrine signaling context necessary for tumorigenicity and metastasis of breast cancer. Cell 145:926-940.
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Chaffer, C.L., Marjanovic, N.D., Lee, T., Bell, G., Kleer, C.G., Reinhardt, F., D’Alessio, A.C., Young, R.A., Weinberg, R.A. (2013). Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity. Cell 154:311-324.
