Dioscaris R. Garcia
Director
Engineering
Materials Science Associates, LLC
United States of America
Biography
Director of Biomedical Research and Operations, Material Science Associates, North Kingston, RI (2014-Present). Associate, Material Science Associates, North Kingston, RI (2013-2014). Consultant, BioIntraface, Inc., North Kingstown, RI (2013-Present). Stein-Bellet Research Fellow Sr. Research Scientist, Rhode Island Hospital, Providence, RI (2013-Present). Characterization of anti-microbial coatings on orthopedic implants. Characterization of bacterial adherence on spinal implant materials. Characterization of bacterial adherence pattern on orthopedic explants. Confocal and Electron Microscopy Bacterial culture Coating synthesis Lead trainer and student supervisor Grant writing Laboratory administration Visiting Scientist, Brown University, Providence, RI (2013-Present). Post Doctoral Scholar, Brown University, Providence, RI (2012-2013). Characterized the calcium signaling kinetics of the Sigma-2 Receptor compounds MV1036A and SN79 and their role in identifying a possible Sigma-2 Receptor subtypes. Served as research instructor for incoming graduate and undergraduate students. Managed laboratory logistics and day to day operations. Generated and edited protocols. Supervised undergraduate research projects. Monitored lab safety and trained incoming laboratory members in the use of laboratory equipment. Senior cell culture and aseptic technique trainer. Teaching Assistant, Brown University, Providence, RI (2006-2011). CEBN0910: Nervous System Function in Health and Disease BIOL1116: Principles of Exercise Physiology BIOL 0800: Principles of Physiology Research Associate, Process Development, Amgen Inc., West Greenwich, RI (2004 – 2005). Characterized Bench-Top Purification Systems for their use as small scale purification systems in the production of Enbrel® (etanercept). Optimized Ultrafiltration/Diafiltration Systems to increase the protein yield from raw product originating from the main production plant. Utilized AKTA Liquid Chromatography. Systems to purify the protein product of the Utrafiltration/Diafiltration Systems. Edited and optimized protocols relating to the use of Bench-Top Purification Systems in the manufacturing of Enbrel® (etanercept). Produced and optimized buffers according to the exact specifications of protocols directly leading towards the production of Enbrel® (etanercept) in both small and large scales. Research Associate, University of Rhode Island, Kingston, RI (2003-2004).
Research Interest
cell signaling and infectious diseases.Molecular Pharmacology,antibiotic-resistant bacteria.