Kevin M. Mcbride
Assistant Professor
Department of Epigenetics and Molecular Carcinogenesis, Divi
MD Anderson Cancer Center
United States of America
Biography
2000: Stony Brook University, Stony Brook, NY, USA, PHD, Molecular and Cellular Pathology 1994: Worcester Polytechnic Institute, Worcester, MA, USA, BS, Biotechnology 2007-2011: Research Associate, Rockefeller University, New York, NY 2002-2007: Postdoctoral Fellow, Rockefeller University, New York, NY 2001-2002: Postdoctoral Associate, Stony Brook University, Stony Brook, NY 2013: MD Anderson Cancer Center, Leukemia SPORE Career Development Award, The University of Texas MD Anderson Cancer Center 2011: University of Texas Systems, STARS Recruitment Award, University of Texas Systems 2003: NIH Postdoctoral Training Fellowship 2002: Aaron Janoff award for excellence in experimental pathology, Stony Brook University
Research Interest
oncology,molecular carcinogenesis, genetics,leukemia
Publications
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Shen HM, Bozek G, Pinkert CA, McBride KM, Wang L, Kenter A, Storb U. Expression of AID transgene is regulated in activated B cells but not in resting B cells and kidney. Mol Immunol 45 (7) :1883-92, 2008.
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McBride KM, Gazumyan A, Woo EM, Schwickert TA, Chait BT, Nussenzweig MC. Regulation of class switch recombination and somatic mutation by AID phosphorylation. J Exp Med 205 (11) :2585-94, 2008
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Dorsett Y, McBride KM, Jankovic M, Gazumyan A, Thai TH, Robbiani DF, Di Virgilio M, Reina San-Martin B, Heidkamp G, Schwickert TA, Eisenreich T, Rajewsky K, Nussenzweig MC. MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation. Immunity 28 (5) :630-8, 2008.
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Robbiani DF, Bunting S, Feldhahn N, Bothmer A, Camps J, Deroubaix S, McBride KM, Klein IA, Stone G, Eisenreich TR, Ried T, Nussenzweig A, Nussenzweig MC. AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations. Mol Cell 36 (4) :631-41, 2009
