Neema Navai
Assistant Professor
Department of Urology
MD Anderson Cancer Center
United States of America
Biography
Dr. Navai is a native of Michigan who completed his undergraduate degree in cellular and molecular biology at the University of Michigan Ann Arbor earning class honors. He then attended the Northwestern University Feinberg School of Medicine in Chicago, IL where he completed his medical doctorate and was admitted to the Alpha Omega Alpha honor society. Dr. Navai remained at Northwestern University for his general surgery internship and urology residency after which he began his time here at MD Anderson as a fellow in the the Urologic Oncology program. Under the mentorship of Drs. Dinney and McConkey, Dr. Navai completed two years of basic science research elucidating molecular signatures of aggressive bladder cancer and successfully competed for the prestigious AUA Foundation Research Scholars grant. Upon completing his fellowship Dr. Navai joined as faculty in the Urology Department where he has already been awarded a Career Development grant from the bladder cancer SPORE to study novel tools aimed at improving current staging shortfalls in muscle invasive bladder cancer through enhanced imaging and molecular profiling. In his role as surgeon scientist Dr. Navai will focus on minimally invasive surgery for aggressive bladder and prostate cancers as well as furthering understanding of the underlying biology of genitourinary malignancies.
Research Interest
Urology, surgery
Publications
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Dinney CP, Fisher MB, Navai N, O'Donnell MA, Cutler D, Abraham A, Young S, Hutchins B, Caceres M, Kishnani N, Sode G, Cullen C, Zhang G, Grossman HB, Kamat AM, Gonzales M, Kincaid M, Ainslie N, Maneval DC, Wszolek MF, Benedict WF Phase I Trial of Intravesical Recombinant Adenovirus Mediated Interferon-α2b Formulated in Syn3 for Bacillus Calmette-Guérin Failures in Nonmuscle Invasive Bladder Cancer. J Urol 190 (3) :850-6, 2013. e-Pub 2013.
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Tran MN, Choi W, Wszolek MF, Navai N, Lee IL, Nitti G, Wen S, Flores ER, Siefker-Radtke A, Czerniak B, Dinney C, Barton M, McConkey DJ The p63 protein isoform ?Np63α inhibits epithelial-mesenchymal transition in human bladder cancer cells: role of MIR-205. J Biol Chem 288 (5) :3275-88, 2013.
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Navai N, Benedict WF, Zhang G, Abraham A, Ainslie N, Shah JB, Grossman HB, Kamat AM, Dinney CP Phase 1b Trial to Evaluate Tissue Response to a Second Dose of Intravesical Recombinant Adenoviral Interferon α2b Formulated in Syn3 for Failures of Bacillus Calmette-Guerin (BCG) Therapy in Nonmuscle Invasive Bladder Cancer. Ann Surg Oncol 23 (12) :4110-4114, 2016