Nupam p. mahajan
Researcher
Deparment of Drug Discovery
Moffitt Cancer Center
United States of America
Biography
Dr. Nupam P. Mahajan is affiliated to Deparment of Drug Discovery, Moffitt Cancer Center. Dr. Nupam P. Mahajan is currently providing services as Researcher. Dr. Nupam P. Mahajan has authored and co-authored multiple peer-reviewed scientific papers and presented works at many national and International conferences. Dr. Nupam P. Mahajan contributions have acclaimed recognition from honourable subject experts around the world. Dr. Nupam P. Mahajan is actively associated with different societies and academies. Dr. Nupam P. Mahajan academic career is decorated with several reputed awards and funding. Dr. Nupam P. Mahajan research interests include is to determine the role of tyrosine kinases in modulating signaling pathways and as epigenetic modifiers in cancer and other diseases..
Research Interest
Is to determine the role of tyrosine kinases in modulating signaling pathways and as epigenetic modifiers in cancer and other diseases.
Publications
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Lawrence HR, Mahajan K, Luo Y, Zhang D, Tindall N, Huseyin M, Gevariya H, Kazi S, Ozcan S, Mahajan NP, Lawrence NJ. Development of novel ACK1/TNK2 inhibitors using a fragment-based approach. Journal of medicinal chemistry. 2015 Mar 17;58(6):2746-63.
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Wu X, Saddiq MZ, Renuse S, Kelkar DS, Barbhuiya MA, Rojas PL, Stearns V, Gabrielson E, Malla P, Sukumar S, Mahajan NP. The non-receptor tyrosine kinase TNK2/ACK1 is a novel therapeutic target in triple negative breast cancer. Oncotarget. 2017 Jan 10;8(2):2971.
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Mahajan K, Malla P, Lawrence HR, Chen Z, Kumar-Sinha C, Malik R, Shukla S, Kim J, Coppola D, Lawrence NJ, Mahajan NP. ACK1/TNK2 Regulates Histone H4 Tyr88-phosphorylation and AR Gene Expression in Castration-Resistant Prostate Cancer. Cancer Cell. 2017 Jun 12;31(6):790-803.
