Punit Kaur
Associate Professor
Microbiology & biochemistry
Morehouse School of Medicine
United States of America
Biography
Punit Kaur is working as an assistant professor in the department of Microbiology, Biochemistry & Immunology at Morehouse School of Medicine. She completed her degree of Doctor from Postgraduate Institute of Medical Education and Research
Research Interest
The goal of our lab is to research and develop heat shock protein-based therapies to be used alone or in combination with current therapies for the eradication of triple-negative breast cancer (TNBC). Recent studies on surface receptors and gene expression of breast tumors have come up with a term TNBC, creating a phenotype and disease quite distinct from that seen in HER2- or ER-positive breast cancers, which is a much more aggressive disease without tumor-specific treatment options. Cancer stem cells (CSC) are cancer cells with characteristics associated with normal stem cells; more specifically they possess the ability to give rise to all cell types found in a particular cancer sample. It is thought that conventional chemotherapies kill differentiated or differentiating cells, which form the bulk of the tumor but are unable to kill new cells
Publications
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Kaur P, Hurwitz M, Zheng H, Nagaraja GM, Bausero MA, Manola J, Asea A. Radiation therapy induces circulating serum heat shock proteins in prostate cancer patients: Clinical findings and laboratory correlates. International J Radia Oncol Biol Phys 2008; 72 (1, Supplement): S63.
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Urueña CP, Cifuentes C, Castañeda DM, Arango AD, Kaur P, Asea AA, Fiorentino S. Petiveria alliacea extracts uses multiple mechanisms to inhibit growth of human and mouse tumoral cells. BMC Complement Altern Med. 2008 Nov 18;8:60. doi: 10.1186/1472-6882-8-60. PMID: 19017389
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Asea A, Jean-Pierre C, Kaur P, Rao P, Linhares IM, Skupski D, Witkin SS. Heat shock protein-containing exosomes in mid-trimester amniotic fluids. J Reprod Immunol. 2008 Oct;79(1):12-7. doi: 10.1016/j.jri.2008.06.001. Epub 2008 Aug 19. PMID: 18715652