Global

Oncology Experts

David N. Danforth

Staff Clinician
Surgery Branch, CCR
National Cancer Institute
United States of America

Biography

Dr. Danforth received his B.A. and M.D. from Northwestern University and his M.S. in physiology from the University of New Mexico. He completed his surgical residency at the New York Hospital-Cornell Medical Center, NYC, NY, and received fellowship training in surgical oncology at the Surgery Branch, National Cancer Institute, NIH, and at the M.D. Anderson Cancer Center, Houston, TX. Additional research training included a senior staff fellowship in the laboratory of Dr. Marc Lippman, NCI. Dr. Danforth’s research efforts are focused primarily on the molecular characteristics of early breast carcinogenesis which are present in normal breast epithelium and their use to develop a molecular signature for risk assessment, and to develop new targets for breast cancer prevention.

Research Interest

Molecular characteristics of breast epithelium, Breast cancer disparities, Breast carcinogenesis, Breast cancer management, Breast cancer prevention, Molecular characteristics of early breast carcinogenesis which are present in normal breast epithelium and their use to develop a molecular signature for risk assessment, Develop new targets for breast cancer prevention, disparities in breast cancer outcome between Caucasian, African American and Hispanic women, especially the molecular basis for these disparities and how they are influenced by health care, socioeconomic and other nonbiologic factors.

Publications

  • Twenty-five year results of the national cancer institute randomized breast conservation trial.

  • Disparities in breast cancer outcomes between Caucasian and African American women: a model for describing the relationship of biological and nonbiological factors.

  • An improved breast epithelial sampling method for molecular profiling and biomarker analysis in women at risk for breast cancer.

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