Fernanda I. Arnaldez
Associate Research Physician
Center for Cancer Research
National Cancer Institute
United States of America
Biography
Dr. Arnaldez is an experienced oncologist with background that includes Government, Industry and Academia. She graduated with high honors from University of Buenos Aires School of Medicine in Buenos Aires, Argentina. She completed residency training at Ricardo Gutierrez Children’s Hospital in Buenos Aires, where she served as Chief Pediatric Resident and ad-honorem attending physician. She came to the US in 2005, where she pursued further training at University of Pittsburgh. She joined the Johns Hopkins University / National Cancer Institute Pediatric Oncology Training Program in 2008, and served as Chief Clinical Fellow in 2011; while pursuing post-doctoral training in the Molecular Oncology Section led by Dr. Lee Helman. She specialized in Solid Tumor Oncology and became Assistant Clinical Investigator at the Center for Cancer Research in 2012. Dr. Arnaldez then joined Novartis Pharmaceuticals Corporation, where she was a Global Clinical Leader in Oncology. She is the recipient of numerous awards, including the Brigid Leventhal Special Merit Award (American Society of Clinical Oncology), Conquer Cancer Foundation Young Investigator Award and American Society of Pediatric Hematology-Oncology Young Investigator Award. She returned to the Center for Cancer Research - NCI as an Associate Research Physician in 2016, where she leads multidisciplinary efforts to develop innovative therapeutic modalities for patients with rare malignancies and pediatric solid tumors. Dr. Arnaldez is the Director of the NIH Pediatric and Wild-Type Gastrointestinal Stromal Tumor Clinic. In 2017, she joined the Investigational Drug Branch of the Cancer Therapy evaluation Program, where she keeps an active portfolio of early phase clinical trials.
Research Interest
pediatric oncology; experimental therapeutics; molecular oncology; clinical research; drug development
Publications
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Yeung CL, Ngo VN, Grohar PJ, Arnaldez FI, Asante A, Wan X, Khan J, Hewitt SM, Khanna C, Staudt LM, Helman LJ. Loss-of-function screen in rhabdomyosarcoma identifies CRKL-YES as a critical signal for tumor growth. Oncogene. 2013 Nov 21;32(47):5429.
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Arnaldez FI, Helman LJ. New strategies in ewing sarcoma: lost in translation?. Clinical Cancer Research. 2014 Jun 15;20(12):3050-6.
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Grohar PJ, Glod J, Peer CJ, Sissung TM, Arnaldez FI, Long L, Figg WD, Whitcomb P, Helman LJ, Widemann BC. A phase I/II trial and pharmacokinetic study of mithramycin in children and adults with refractory Ewing sarcoma and EWS–FLI1 fusion transcript. Cancer Chemotherapy and Pharmacology. 2017 Jul 22:1-8.