Keqiang Chen

Biography

Dr. Keqiang Chen obtained his Ph.D. degree in Etiologic Biology from the Second Military Medical University, Shanghai, China, in 2001. In 2002-2003, Dr. Chen studied as a Postdoctoral Fellow at the Medical Center at University of Rochester, NY, USA. In 2004, Dr. Chen joined Dr. Ji Ming Wang’s laboratory in Cancer and Inflammation Program at NCI-Frederick as a Visiting Fellow. In September 2009, Dr. Chen was promoted to the position of Research Fellow at NCI-Frederick. From November 2012, Dr. Chen worked as a Research Scientist at the Department of Biological Sciences, College of Sciences, Virginia Polytechnic Institute and State University (Virginia Tech), in Blacksburg, VA. Dr. Chen was recruited as a Staff Scientist to the Cancer and Inflammation Program, Center for Cancer Research, NCI-Frederick, in June 2016, pursuing his studies of chemoattractant GPCRs in inflammation, immune responses and cancer.

Research Interest

Current research focuses on three major areas to elucidate: 1) the mechanisms by which chemoattractant GPCRs contribute to colonic epithelial homeostasis, inflammation, and tumorigenesis; 2) the mechanisms by which chemoattractant GPCRs regulate the function of myeloid cells in inflammation and anti-tumor host defense; 3) the mechanisms by which chemoattractant GPCRs regulate host and microbiome interaction, 4) leukocyte trafficking 5) chemoattractant GPCR regulation and signaling 6) mouse models of inflammation and cancer.