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Kyung S. Lee

Senior Investigator
Center for Cancer Research
National Cancer Institute
United States of America

Biography

Dr. Kyung Lee received his Ph.D. in 1994 from the Department of Biochemistry at the Johns Hopkins University in Baltimore. He then worked with Raymond Erikson at Harvard University as a postdoctoral fellow and studied in the fields of protein kinase and cancer. In 1998, he joined NIH as a tenure-track investigator in the Laboratory of Metabolism at NCI. In 2005, Dr. Lee became a senior investigator and head of the Chemistry Section, Laboratory of Metabolism. Dr. Lee is the recipient of an NCI Intramural Research Award, a Society for Biomedical Research CKD Award, and several Federal Technology Transfer Awards for his inventions and patents related to Plk1. He serves as an academic editor for PLoS ONE and an editorial board member for the Journal of Biological Chemistry.

Research Interest

1) cell cycle, 2) centrosome, 3) mitosis, 4) protein kinase, 5) anti-cancer therapy

Publications

  • Soung NK, Park JE, Yu LR, Lee KH, Lee JM, Bang JK, Veenstra TD, Rhee K, Lee KS. Plk1-dependent and-independent roles of an ODF2 splice variant, hCenexin1, at the centrosome of somatic cells. Developmental cell. 2009 Apr 21;16(4):539-50.

  • Kang YH, Park JE, Yu LR, Soung NK, Yun SM, Bang JK, Seong YS, Yu H, Garfield S, Veenstra TD, Lee KS. Self-regulated Plk1 recruitment to kinetochores by the Plk1-PBIP1 interaction is critical for proper chromosome segregation. Molecular cell. 2006 Nov 3;24(3):409-22.

  • Kang YH, Park JE, Yu LR, Soung NK, Yun SM, Bang JK, Seong YS, Yu H, Garfield S, Veenstra TD, Lee KS. Self-regulated Plk1 recruitment to kinetochores by the Plk1-PBIP1 interaction is critical for proper chromosome segregation. Molecular cell. 2006 Nov 3;24(3):409-22.

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